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Typical examples of a subacutecourse are vertebral osteomyelitis due to tuberculosis or brucellosis on the one hand, ordelayed implant-associated infections, mainly caused by low-virulence microorganisms(coagulase-negative staphylococci, Propionibacterium acnes) on the other hand [15, 27].Chronic osteomyelitis is observed in case of insufficient therapy leading to persistence orrecurrence.
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